Vascular Dementia Conference 2023 | Vascular Dementia Congress | Alzheimer | Paris | France

Dementia Pathophysiology

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Vascular disease is mainly caused by hardening of the arteries (atherosclerosis) due to a thickening of the artery lining from fatty deposits or plaques (atheroma).

Vascular disease may manifest acutely when thrombi, emboli, or acute trauma compromises perfusion. Thrombosis are often of an athermanous nature and occur in the lower extremities more frequently than in the upper extremities. Multiple factors predispose patients for thrombosis. These factors include sepsis, hypotension, low cardiac output, aneurysms, aortic dissection, bypass grafts, and underlying atherosclerotic narrowing of the arterial lumen.

Peripheral artery disease
Aneurysm
Amyloid cascade and tau pathology
Vascular pathology in aging brain
Protein trafficking and synaptic pathology
White matter pathology in vascular cogitive disease
Hippocampal pathology in aged
Retinal pathology in susac syndrome
Cerebral amyloid angiopathy

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