Boon Chuan Low
National University of Singapore, Singapore
Biography
Prof. Boon Chuan LOW is a Principal Investigator at the Mechanobiology Institute and Department of Biological Sciences, National University of Singapore. His group focuses on defining cellular and molecular mechanisms underlying neuronal differentiation and cancer metastasis. His discovery on the BCH domain as a versatile protein scaffold has led to our better understanding of the intricate spatiotemporal regulation of GTPases, kinases and metabolic signaling in cell morphogenesis, cell motility, cell growth and differentiation. His work also extends to BCH and other scaffold proteins that can integrate both biochemical and mechanical signals in cell-cell and cell- matrix interaction, leading to tissue organization and organogenesis.